Proteostasis Coming Up Short on New CF Treatment According to Sahm Adrangi

Sahm Adrangi and Kerrisdale Capital are widely known in the investment world for their ability to successfully pick companies on a value basis in which to short. Over the years, Sahm Adrangi has picked quite a few pharmaceutical companies to short whose products were in the testing phases. These medications and treatments were all being marketed in a misleading way that implied a much higher level of success in treatment than actually existed.

Proteostasis Pharmaceuticals is the newest company that Sahm Adrangi has set his sites on and is encouraging others to do the same. The main drug being developed by Proteostasis is known as PTI-428 and it is being developed for the treatment of the devastating disease of cystic fibrosis. Unfortunately for the patients that suffer from the disease, Sahm Adrangi doesn’t believe that the drug shows much promise to improve their condition in any significant way.

Sahm Adrangi and Kerrisdale perform their own research on the companies that they are planning on investing in, or against. When researching the drug being tested by Proteostasis, they found that it is most likely almost completely ineffective for the treatment of the disease. The data that was released by Proteostasis was very low-quality and omitted many important things.

When the Food and Drug Administration gave the medication an “orphaned drug” status, the stock of the company almost doubled. This status is granted to drugs that are being developed for diseases with very few treatment options available. It allows these medications to be fast-tracked for approval. While this is a great program for medications that are truly effective in helping the patients with these hard to treat diseases, it can sometimes lead to companies releasing information that is less than accurate to investors and the public.

This news is not only disappointing for those who invested in the success of the drug that is still in testing phases, but also to the patients that were tracking its progress in hopes to treat their debilitating illness. Kerrisdale expects the stocks to drop after the next round of testing data is released. If so, they will benefit from the drop in price.

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Eric Lefkofsky Working to Enhance the Quality of Life

Eric Lefkofsky aims to enhance the quality of life for human beings through the Lefkofsky Family Foundation that he cofounded with his wife Liz. Eric Lefkofsky, a graduate of the University of Michigan, found success in the business world through hard work and dedication and recognizes the need to utilize the benefits of his success to help others. He co-founded Tempus, which is a technology company that focuses on assisting doctors in personalizing treatment for cancer through the use of analytics and data. In addition to Tempus technology making data more readily available to doctors and patients, it also makes data available to researchers who are conducting lifesaving research on a daily basis. The overarching goal of Tempus is to enhance the quality of life of cancer patients. This mirrors the stated goal of the Lefkofsky Family Foundation, which is to enhance the quality of life for all humans.

The Lefkofsky Family Foundation started its mission in 2006, striving to enhance the quality of human life through four specific missions. The first mission is to ensure that children have access to quality education, with a special emphasis on assisting middle school aged children. The second mission is to help girls in vulnerable communities by ensuring that their inherent human rights are protected. The third mission is to assist innovative medical research to help those afflicted with terrible diseases such as cancer. Finally, the fourth mission of the Lefkofsky Family Foundation is to assist cultural initiatives, which helps foster a sense of community among those from different cultures. All four of these missions help propel the quality of life of all humans, whether they are directly or indirectly benefitted from the foundation. Eric Lefkofsky and his family has suffered loss in the past and they have decided to use their time and resources to help prevent further suffering and improve the quality of life for all humans.

Wes Edens, Sports and Commuting

Wes Edens is a widely known professional who is in charge of Brightline. This is a private train that’s a component of the comprehensive passenger rail network within the United States at the moment. Brightline is recently becoming a strong choice for people who do a lot of traveling for work in the state of Florida. It helps people who need to get from Fort Lauderdale to Miami and vice versa. People who have to go from one of these communities to the other often have many difficulties with the process. It can be a time-consuming affair for anyone. Brightline is at the helm of trains that can accommodate people with their Fort Lauderdale and Miami travel requirements numerous times on a daily basis. Busy people who don’t even want to have to think about getting behind the wheel can turn to Brightline with ease.

Fortress Investment Group is Brightline’s owner. Wes Edens is a big executive on the Fortress Investment Group team, too. He’s an Oregon State University alumnus who wants to do anything in his capacity to make transportations within the United States a lot more streamlined. He has his sights set on some major United States metropolises as well. These include Houston and Dallas in Texas. He wants to simplify transportation processes for people who are in these cities.

Wes Edens is now working with Nassef Sawiris from the Middle Eastern nation of Egypt. They’ve come to a major decision as a pair. They’re purchasing Aston Villa majority stakes. This is the name of a soccer team that hails from England in the United Kingdom. Tony Xia is the individual who acquired it a couple of years ago. He’s an entrepreneur who comes from China. He has landed a Co-Chairman position. He’s going to stay involved with its board as well.

Wes Edens handles many different matters that pertain to investments that are within the private equity realm. He has a zeal for all kinds of sports, too. He’s the Milwaukee Bucks’ ardent co-owner. This is a basketball team that has a massive national presence in America. Nassef Sawiris and Wes Edens buy Aston Villa controlling stake

Louis Chênevert Helped to Change the Aerospace Industry

Louis Chênevert may have come from relatively humble beginnings, but he has achieved an enormous level of success in the business world. The native was born in Montreal, Quebec 1958 and started to become interested in the world of business at a very early age. He knew that it wasn’t going to be easy to achieve his goals, but this didn’t matter to Louis Chênevert. He became dedicated to success despite the hard work that he knew would lay ahead of him. His current position of Chief Executive Officer of United Technologies was only acquired after many years of hard work and dedication.

At the University of Montreal, Louis Chênevert earned a degree in production management. With this field of study, Louis Chênevert was taught how to ensure that the manufacturing process is running efficiently and producing products with high quality. In order for a manufacturing company to be successful, they must ensure that production is managed properly.

Before Louis Chênevert’s position at United Technologies, UTC, came after working for General Motors for 14 years. While he truly enjoyed his time in manufacturing, he decided that it was time for a change in his career and made the switch to aerospace. This is when he began working with one of the companies contained within United Technologies Corporation. Over the years, the quickly moved up through the ranks and eventually became the CEO and president of UTC.

During his time at these subsidiaries that produced aircraft engines, he managed to increase the manufacturing efficiency a considerable amount. When he began working for UTC directly, it was a big change with a lot more responsibility. While the smaller companies contained within that Louis Chênevert had worked for focused only on aircraft engines, UTC itself produced a much larger variety of products including elevators, escalators, security systems, and HVAC systems. One of his biggest accomplishments at UTC was his insistence in investing into the revolutionary GTF engine. While many people criticized this move as it was a costly investment, it has paid off greatly for the company over the years.

https://www.crunchbase.com/person/louis-r-chenevert#/entity

Robert Deignan – Hard Work Makes Dreams Come True

Robert Deignan is the co founder and Chief Executive Officer of ATS Digital Services. ATS Digital Services is a company that can support every single one of your digital support needs. From a faulty network connection, to a slow home computer, ATS Digital Services is there to help you, and that is all because Robert Deignan had the guts and put in the hard work to create the company.

Deignan attended Purdue University from 1992 to 1995 and graduated with a Bachelors of Science in Business Management and Organizational Leadership. After graduating, he realized that his dream was to be a business owner and entrepreneur. With that in mind, he put his head down and started working hard. He needed that real world experience if he wanted a well rounded education.

He had a dream, and he knew he had to work to achieve it, so he got his hands dirty, and started learning what it took to make a successful business. Only three years after graduating, Robert Deignan co founded his very first business, Fanlink. After only another three years at Fanlink, he moved on to iS3 becoming their Executive Vice President. Both these companies had a passion for technology, and helped Deignan round out his knowledge even further.

In August of 2011, Robert Deignan helped co found ATS Digital Services LLC, and became its Chief Executive Officer. He used his experience as a vice president, and his previous knowledge of founding a company, to help get ATS Digital Services off the ground, and running.

Deignan has almost twenty years of technology business experience that he puts in ATS Digital Services everyday. The idea for the business came from a couple different places. Part of the inspiration was his previous work at an Anti-Malware Software Company, where the company ran into technical issues, and solved it through excellent customer service. When he moved on from this company, Robert Deignan realized that utilizing remote connection technology to provide digital support to customers, was a great opportunity to fill a gap in the market. It would help customers, and their business.

http://www.prweb.com/releases/2017/07/prweb14550762.htm